New Monoclonal Antibody Prevents RSV in Infants and Toddlers

• 2023

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• Diane Aschenbrenner
PMID: 37732664DOI: https://dx.doi.org/10.1097/01.NAJ.0000979076.37269.a5

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This article discusses the approval of the monoclonal antibody nirsevimab-alip (Beyfortus) to prevent respiratory syncytial virus (RSV) in high-risk neonates and infants up to 24 months old. It emphasizes that this antibody, given via injection at the start of the RSV season, helps reduce the risk of severe RSV symptoms. The safety and effectiveness of nirsevimab-alip were supported by three clinical trials, showing a decrease in medically attended RSV lower respiratory tract infections. However, caution is advised due to potential serious hypersensitivity reactions. This development is significant for vulnerable children at risk of severe RSV disease.

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Tags

Focus Area: Infectious Disease

Audiences: Nurses; Physicians

Emergency Management Stage: Preparedness (Prevention / Protection)

Collection: Nirsevimab Library

Keywords: Antibodies, Monoclonal; Child, Preschool; Infant; Respiratory Syncytial Viruses; Virus Diseases; Respiratory Syncytial Virus Vaccines

Institutions: Johns Hopkins School of Nursing; Johns Hopkins University

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