Preventative Therapies for Respiratory Syncytial Virus (RSV) in Children: Where Are We Now?

• 2024

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• Marie-Hélène Bourassa; Larry Lands
PMID: 37704463DOI: https://dx.doi.org/10.1016/j.prrv.2023.08.005

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This article reviews the current landscape of preventative therapies for respiratory syncytial virus (RSV) in children, focusing on the prefusion F protein as a key target for immunization. It reviews past and ongoing research efforts, including monoclonal antibodies, maternal immunization, and vaccines. The challenges of preventing RSV infections in pediatric patients are addressed, highlighting the importance of advancing immunization strategies to reduce the significant healthcare burden caused by RSV worldwide.

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Tags

Focus Area: Infectious Disease

Audience: Physicians

Emergency Management Stage: Preparedness (Prevention / Protection)

Collection: Nirsevimab Library

Keywords: Antibodies, Viral; Child; Child, Preschool; Immunization; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; Antibodies, Neutralizing; Respiratory Syncytial Virus Vaccines

Institutions: Montreal Children's Hospital; McGill University

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