Prevention and Treatment Strategies for Respiratory Syncytial Virus (RSV)

• 2023

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• Dvir Gatt; Isaac Martin; Rawan AlFouzan; Theo Moraes
PMID: 36839426DOI: https://dx.doi.org/10.3390/pathogens12020154

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About

The article discusses prevention and treatment strategies for respiratory syncytial virus (RSV), a major cause of severe lower respiratory tract disease, especially in young children. Despite the lack of an approved RSV vaccine, advancements have been made in understanding RSV pathogenesis and immunopathology, leading to new prevention strategies. The review covers current treatment options for acute RSV disease, including specific therapies like ribavirin and monoclonal antibodies, as well as non-specific treatments like mucolytics and bronchodilators. Future directions include the development of RSV vaccines and long-acting monoclonal antibodies to improve prevention efforts. The article emphasizes the importance of prevention over treatment and the need for effective strategies to address the global burden of RSV.

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Tags

Focus Area: Infectious Disease

Audience: Physicians

Emergency Management Stage: Preparedness (Prevention / Protection)

Bundles: Nirsevimab Library

Keywords: Antibodies, Monoclonal; Antiviral Agents; Bronchiolitis; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Therapeutics; Respiratory Syncytial Virus Vaccines

Institutions: The Hospital for Sick Children (SickKids)

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