Introduction to This JPIDS Supplement: All Infant Protection Against Serious RSV Disease

• 2024

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• Joseph Domachowske
PMID: 38995084DOI: https://doi.org/10.1093/jpids/piae037

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This article describes the challenges and advancements in protecting infants from serious RSV disease. It highlights the unpredictability of RSV, especially during the COVID-19 pandemic, and notes that most infants are infected in their first year. New prevention methods include a monoclonal antibody called nirsevimab and a maternal vaccine approved by the FDA in 2023. These innovations aim to protect all infants rather than just high-risk groups. The supplement includes expert reviews on drug approval processes, transplacental antibody transfer, passive immunization strategies, and how COVID-19 affected RSV patterns.

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Tags

Focus Area: Infectious Disease

Audience: Physicians

Emergency Management Stage: Preparedness (Prevention / Protection)

Bundle: Nirsevimab Library

Keywords: Antibodies, Monoclonal; Infant, Newborn; Public Health; Respiratory Syncytial Virus Infections; United States Food and Drug Administration; Vaccines

Institutions: State University of New York - Upstate Medical University

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Respiratory Syncytial Virus-An Update for Prenatal and Primary Health Providers 2023 · University of Washington, State University of New York - Upstate Medical University, Seattle Children's Hospital New and Emerging Passive Immunization Strategies for the Prevention of RSV Infection During Infancy 2024 · State University of New York - Upstate Medical University Introduction to This JPIDS Supplement: All Infant Protection Against Serious RSV Disease 2024 · State University of New York - Upstate Medical University

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