Effect of Palivizumab Prophylaxis on Respiratory Syncytial Virus Infection in Very Preterm Infants in the First Year of Life in The Netherlands

• 2023

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• Rutger Schepp; Joanna Kaczorowska; Pieter van Gageldonk; Elsbeth Rouers; Elisabeth Sanders; Patricia Bruijning-Verhagen
PMID: 38140212DOI: https://dx.doi.org/10.3390/vaccines11121807

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This article describes a study about using palivizumab to prevent RSV infections. It focuses on very preterm infants during their first year. The research took place in the Netherlands and aimed to see if this treatment could lower infection rates. The article concludes that palivizumab reduces RSV infection in very premature infants, but future research should look at clinical implications and reasons for non-compliance, and compare palivizumab with emerging prophylactics like nirsevimab.

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Tags

Focus Area: Infectious Disease

Audience: Physicians

Emergency Management Stage: Preparedness (Prevention / Protection)

Collection: Nirsevimab Library

Keywords: Netherlands; Respiratory Syncytial Virus Infections; Palivizumab; Infant, Premature

Institutions: National Institute for Public Health and the Environment; University Medical Center Utrecht; Wilhelmina Children's Hospital

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